To begin with, space and time, once they are set, are a primary means to individuate and identify objects, people, relations, processes, and events. Location and bounding are important if not vital attributes for the definition of the objects, events and relationships existing in the world around us. To choose one ordering principle rather than another is to choose a particular spatio-temporal framework for describing the world. The choice is not neutral with respect to what we can describe. The absolute theory of space and time always forces us into a framework of mechanistic descriptions, for example that conceal from view important properties of the world (such as those of living organisms) that stand only to be revealed by a relational view. To choose the wrong framework is to misidentify elements of the world around us.
David Harvey, (1996) Justice, Nature & the Geography of Distance p. 264